Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 7, Pages 3491-3499Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b02977
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Funding
- National Science Foundation of China [21572117]
- State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences [GTZK201405]
- Peking Union Medical College [GTZK201405]
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An efficient, green, and novel method for the synthesis of N-heterocycle-fused quinoxalines is repotted herein. Dimethyl sulfoxide was used as both a reactant and a solvent in this reaction. A wide range of products in moderate to excellent yields were obtained, including pyrrolo[1,2-a]quinoxalines, indolo[1,2-a]quinoxalines, 1H-pyrrolo[3,2-c]quinoliries, and benzo [4,5]imidazo [1,2-c] quinazolines.
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