Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 1, Pages 469-477Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b02588
Keywords
-
Categories
Funding
- NIHGMS [R01GM120162]
- NSF
Ask authors/readers for more resources
Esters are valuable electrophiles for cross coupling due to their ubiquity and ease of synthesis. However, I harsh conditions are traditionally required for the effective cross-coupling of ester substrates. Utilizing a recently discovered precatalyst, Pd-catalyzed Suzuki-Miyaura and Buchwald- Hartwig reactions involving cleavage of the C(acyl)-O bond of aryl esters that proceed under mild conditions are reported. The Pd(II) precatalyst is highly active because it is reduced to the Pd(0) active species more rapidly than previous precatalysts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available