Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 82, Issue 16, Pages 8733-8742Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01288
Keywords
-
Categories
Funding
- JSPS KAKENHI [A16H010260, A262880510, T15K149760, T15KT00630]
- Ministry of Education, Culture, Sports, Science, and Technology, Japan (MEXT)
- JST ACT-C, Japan [JPMJCR12YM]
- Grants-in-Aid for Scientific Research [15H04632, 15KT0063, 16H01026] Funding Source: KAKEN
Ask authors/readers for more resources
Cycloisomerization is an atom economic procedure that converts dienes and enynes into cyclic molecules. To date, cycloisomerization between enamides and silylalkynes has not been explored. We found that N-acyl-N-vinyl-2-silylalkynylaniline derivatives undergo a cycloisomerization in the presence of a well-defined ruthenium hydride to give a 2,3-disubstitued indole. The vinyl and silylmethyl substituents on the 2- and 3-positions of the indole can be easily converted to other functional groups.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available