Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 58, Issue 11, Pages 1727-1732Publisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.117.191635
Keywords
molecular imaging; infection; anti-microbial; optical imaging
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Metabolic imaging has come to occupy a prominent place in the diagnosis and management of microbial infection. Molecular probes available for infection imaging have undergone a rapid evolution starting with nonspecific agents that accumulate similarly in infection, sterile inflammation, and neoplastic tissue and then extending to more targeted probes that seek to identify specific microbial species. This focus review describes the metabolic and molecular imaging techniques currently available for clinical use in infection imaging and those that have demonstrated promising results in preclinical studies with the potential for clinical applications.
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