Journal
CHEMICAL COMMUNICATIONS
Volume 55, Issue 86, Pages 12936-12939Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc07068k
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Funding
- Spanish Government [CTQ2015-64561-R, RTI2018-095038-B-I00]
- European Structural Funds [S2018/NMT-4367]
- Universidad Autonoma de Madrid
- CONACYT-Mexico
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A simple and general conjugate nucleophilic halogenation is presented. The THTO/halosilane combination has shown the ability to act as a nucleophilic halide source in the conjugate addition to a variety of Michael acceptors. In addition, a straightforward diastereoselective halogen installation using alpha,beta-unsaturated acyloxazolidinones as platforms has been developed.
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