Journal
THERANOSTICS
Volume 9, Issue 26, Pages 8026-8047Publisher
IVYSPRING INT PUBL
DOI: 10.7150/thno.38261
Keywords
drug delivery; nanomedicine; cancer starvation therapy; combination treatment
Categories
Funding
- National Natural Science Foundation of China [NSFC 51773199]
- Hangzhou Normal University [4095C5021920450]
Ask authors/readers for more resources
Abnormal cell metabolism with vigorous nutrition consumption is one of the major physiological characteristics of cancers. As such, the strategy of cancer starvation therapy through blocking the blood supply, depleting glucose/oxygen and other critical nutrients of tumors has been widely studied to be an attractive way for cancer treatment. However, several undesirable properties of these agents, such as low targeting efficacy, undesired systemic side effects, elevated tumor hypoxia, induced drug resistance, and increased tumor metastasis risk, limit their future applications. The recent development of starving-nanotherapeutics combined with other therapeutic methods displayed the promising potential for overcoming the above drawbacks. This review highlights the recent advances of nanotherapeutic-based cancer starvation therapy and discusses the challenges and future prospects of these anticancer strategies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available