Journal
JOURNAL OF NEUROSURGERY-PEDIATRICS
Volume 20, Issue 1, Pages 51-55Publisher
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2017.2.PEDS16679
Keywords
GOPC; ROSI; receptor protein-tyrosine kinases; 6q22 deletion; oncology
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Pediatric high-grade glioma is a rare tumor characterized by high mortality. The authors report the first case of a high-grade glioma associated with aGOPC(FIG)-ROSI fusion in a pediatric patient. The patient underwent gross-total resection at the age of 4 years, followed by adjuvant high-dose chemotherapy and autologous hematopoietic stem cell rescue. At 30 months after transplantation, she remains disease free.
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