Journal
NEW JOURNAL OF CHEMISTRY
Volume 43, Issue 42, Pages 16612-16620Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9nj03727f
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Funding
- HKUST-CIL Joint Laboratory of Innovative Environmental Health Technologies and Hong Kong Research Grant Council [E-HKUST601/17]
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In this study, we investigated the antibacterial properties of nanostructured Ag@SiO2-penicillin synthesized from triangular silver nanoplates (Ag NPs) against methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) bacteria. The Ag@SiO2-penicillin nanoparticles contained approximately 33.2 wt% Ag as determined by ICP-OES. Grafting of about 2.8 wt% penicillin on Ag@SiO2 remarkably enhanced the bactericidal properties against MSSA and MRSA bacteria and showed no cell-death inducing effects towards the A431 cell line.
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