4.7 Article

Artocarmins G-M, Prenylated 4-Chromenones from the Stems of Artocarpus rigida and Their Tyrosinase Inhibitory Activities

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 80, Issue 12, Pages 3173-3179

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.7b00453

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Funding

  1. Vietnam National University-Ho Chi Minh City [A2015-18-02]

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Phytochemical analysis of an EtOAc extract of the stems of Artocarpus rigida led to the identification of seven new prenylated 4-chromenones, artocarmins G-M (1-7), and nine known compounds (8-17). Their structures were identified based on physical data analysis. In the tyrosinase inhibitory activity test, norartocarpetin (8) displayed the strongest effect, with an IC50 value of 0.023 mu M.

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