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Bacterial γ-glutamyltranspeptidase: Food and medicinal applications

Journal

SCIENCEASIA
Volume 45, Issue 6, Pages 503-508

Publisher

SCIENCE SOCIETY THAILAND
DOI: 10.2306/scienceasia1513-1874.2019.45.503

Keywords

glutathione; gamma-glutamyl transferase; gamma-glutamyl transpeptidase; gamma-glutamyl linkage

Funding

  1. Ministry of Education, Science and Technology, Japan

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gamma-Glutamyltranspeptidase (GGT) catalyzes the hydrolysis of gamma-glutamyl compounds and the transfer of their gamma-glutamyl moiety to another amino acids or peptides. We have proposed several applications of this enzyme, especially in food and medicine, for the wellness of humans. These applications depend on the fact that the pH optima of the hydrolysis and transpeptidase reactions are distinctly different in E. coli GGT. The applications of bacterial GGTs are introduced in this review.

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