4.1 Article

Mucosal bacterial dissemination in a rhesus macaque model of experimental brucellosis

Journal

JOURNAL OF MEDICAL PRIMATOLOGY
Volume 47, Issue 1, Pages 75-77

Publisher

WILEY
DOI: 10.1111/jmp.12282

Keywords

aerosol exposure; Brucella melitensis; mucosal dissemination; rhesus macaque

Funding

  1. NIH [5 U54 AI057156]
  2. TNPRC base grant (NIH) [P51-OD11104]

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Animals were experimentally infected with Brucella melitensis via aerosol. B.melitensis was cultured from the saliva and vaginal vault of infected animals, corresponding to bacterial dissemination in other target tissues. This is the first report of bacterial dissemination to these mucosal surfaces in a non-human primate model of brucellosis.

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