Journal
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY
Volume 17, Issue 1, Pages -Publisher
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S021951941750018X
Keywords
FSI; CFD; cerebral aneurysm; rupture risk factor; hypertension
Categories
Funding
- FONDECYT [111008]
- Center for Mathematical Modeling of Universidad de Chile [PFB03 2007]
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Fluid-structure interaction (FSI) simulations were carried out in a human cerebral aneurysm model with the objective of quantifying the effects of hypertension and pressure gradient on the behavior of fluid and solid mechanics. Six FSI simulations were conducted using a hyperelastic Mooney-Rivlin model. Important differences in wall shear stress (WSS), wall displacements, and effective von Mises stress are reported. The hypertension increases wall stress and displacements in the aneurysm region; however, the effects of hypertension on the hemodynamics in the aneurysm region were small. The pressure gradient affects the WSS in the aneurysm and also the displacement and wall stress on the aneurysm. Maximum wall stress with hypertension in the range of rupture strength was found.
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