Journal
NON-CODING RNA RESEARCH
Volume 4, Issue 3, Pages 82-85Publisher
KEAI PUBLISHING LTD
DOI: 10.1016/j.ncrna.2019.09.001
Keywords
miRNAs; Non-coding RNAs; miRNA-based therapy; Drug resistance
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Non-coding RNAs (ncRNAs) have long been considered as junk material of the human genome until functional studies have exposed them as critical regulators of gene expression in both physiological and pathological conditions. Mounting evidences have also shown that ncRNAs may serve as diagnostic markers for several disorders, predictor for drugs response, and targets for new therapeutic approaches. In this mini-review, we discuss the state of the art of non-coding RNAs in drug development and their involvement in conventional treatments response.
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