Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 7, Issue 48, Pages 7723-7728Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9tb01645g
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Funding
- National Natural Science Foundation of China [21431002, 21871122]
- Fundamental Research Funds for the Central Universities [lzujbky-2018-kb12]
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Herein, we presented a hydrosoluble triple-site and triple-excitation alternative NIR fluorescent probe for visualization of endogenous biothiols in phosphate-buffered saline (pH 7.4, 10 mM). Upon irradiation using different excitation light, probe 1 exhibited different fluorescence responses upon the addition of Cys, Hcy, and GSH: lambda(ex) = 419 nm, lambda(em) = 498 nm; lambda(ex) = 518 nm, lambda(em) = 573, 616, 727, and 783 nm; lambda(ex) = 555 nm, lambda(em) = 612 and 727 nm, respectively. Furthermore, 1 was favourably applied for bioimaging endogenous Cys, Hcy, and GSH in A375 cells through well-defined blue-green-red emission channels.
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