Journal
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Volume 441, Issue -, Pages 6-13Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmmm.2017.05.039
Keywords
Nanoparticles; Magnetite; Magnetic resonance imaging
Funding
- Ministry of Education and Science of the Russian Federation [14.607.21.0132, RFMEFI60715X0132]
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Magnetic nanoparticle size is one of the key factors determining its magnetic and biological properties. Herein, we report a synthesis of magnetite uniform-sized cubic nanoparticles with 10, 15 and 20 nm edge lengths for magnetic resonance imaging (MRI). The structure and physicochemical properties of obtained magnetite nanocubes (MNCbs) were studied by multiple methods. MNCbs conjugated with Pluronic F-127 exhibited high colloidal stability in aqueous medium. Synthesized MNCbs demonstrated improved T-2-relaxation comparing to commercially available contrast agents proving that these nanocubes can be used for MRI. (C) 2017 Elsevier B.V. All rights reserved.
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