4.6 Article

Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Auvro R. Mridha et al.

JOURNAL OF HEPATOLOGY (2017)

Review Endocrinology & Metabolism

The Role of Cholesterol in the Pathogenesis of NASH

George N. Ioannou

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2016)

Article Chemistry, Multidisciplinary

Formation of 3D Cholesterol Crystals from 2D Nucleation Sites in Lipid Bilayer Membranes: Implications for Atherosclerosis

Neta Varsano et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Biochemistry & Molecular Biology

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll et al.

NATURE MEDICINE (2015)

Article Gastroenterology & Hepatology

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

Christopher Savard et al.

HEPATOLOGY (2013)

Article Gastroenterology & Hepatology

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome

Derrick M. Van Rooyen et al.

JOURNAL OF HEPATOLOGY (2013)

Article Biochemistry & Molecular Biology

Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis

George N. Ioannou et al.

JOURNAL OF LIPID RESEARCH (2013)

Review Biochemistry & Molecular Biology

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

Giovanni Musso et al.

PROGRESS IN LIPID RESEARCH (2013)

Article Gastroenterology & Hepatology

Atorvastatin and Antioxidants for the Treatment of Nonalcoholic Fatty Liver Disease: The St Francis Heart Study Randomized Clinical Trial

Temitope Foster et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis

Derrick M. van Rooyen et al.

GASTROENTEROLOGY (2011)

Review Immunology

Caspase-1-induced pyroptotic cell death

Edward A. Miao et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Gastroenterology & Hepatology

Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease

Hyohun Park et al.

JOURNAL OF GASTROENTEROLOGY (2011)

Article Biochemistry & Molecular Biology

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

Savitha Subramanian et al.

JOURNAL OF LIPID RESEARCH (2011)

Article Multidisciplinary Sciences

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

Stacy M. Horner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Gastroenterology & Hepatology

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

Michal Ganz et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Article Gastroenterology & Hepatology

Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study

Masato Yoneda et al.

HEPATOLOGY RESEARCH (2010)

Article Gastroenterology & Hepatology

A Pilot Study Using Simvastatin in the Treatment of Nonalcoholic Steatohepatitis A Randomized Placebo-controlled Trial

Austin Nelson et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2009)

Article Cell Biology

Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

Abigail S. Haka et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Pharmacology & Pharmacy

Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice

Shuqin Zheng et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Article Multidisciplinary Sciences

The Nalp3 inflammasome is essential for the development of silicosis

Suzanne L. Cassel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

Catherine Dostert et al.

SCIENCE (2008)

Article Endocrinology & Metabolism

Adipocyte death, adipose tissue remodeling, and obesity complications

Katherine J. Strissel et al.

DIABETES (2007)

Article Gastroenterology & Hepatology

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet

Naoto Matsuzawa et al.

HEPATOLOGY (2007)

Article Gastroenterology & Hepatology

A lipidomic analysis of nonalcoholic fatty liver disease

Puneet Puri et al.

HEPATOLOGY (2007)

Article Medicine, General & Internal

Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study

Vasilios G. Athyros et al.

CURRENT MEDICAL RESEARCH AND OPINION (2006)

Article Multidisciplinary Sciences

Gout-associated uric acid crystals activate the NALP3 inflammasome

F Martinon et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

S Cinti et al.

JOURNAL OF LIPID RESEARCH (2005)

Article Gastroenterology & Hepatology

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

DE Kleiner et al.

HEPATOLOGY (2005)

Article Medicine, Research & Experimental

Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

I Tabas

JOURNAL OF CLINICAL INVESTIGATION (2002)