Journal
JOURNAL OF LIGHTWAVE TECHNOLOGY
Volume 35, Issue 21, Pages 4747-4751Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JLT.2017.2761738
Keywords
Photonic crystal fibers; optical fiber devices; optical fiber interferometer; optical fiber sensors
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We present an all-fiber Mach-Zehnder modal interferometer based on a special photonic crystal fiber taper and its performance as a transducer for biological sensing. The sensor showed refractive index sensitivity around 722.3 nm/RIU for measurements between 1.30864 and 1.32014 RIU. We investigated the interferometer as a transducer for an immunosensor system after immobilization of an antigen over the activated taper waist, where it detected the interaction between antigen and antibody achieving a record detection limit of 125 pg/ml of antibody concentration. This extra low detection limit allows the modal interferometer to be used in biosensing applications, such as disease diagnosis, or in the food industry.
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