Journal
DIABETES
Volume 64, Issue 7, Pages 2369-2375Publisher
AMER DIABETES ASSOC
DOI: 10.2337/db15-0203
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Funding
- National Institute of General Medical Sciences, National Institutes of Health [DP2-OD-007288]
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Brown and beige adipose tissue is specialized for heat production and can be activated to reduce obesity and metabolic dysfunction in animals. Recent studies also have indicated that human brown fat activity levels correlate with leanness. This has revitalized interest in brown fat biology and has driven the discovery of many new regulators of brown fat development and function. This review summarizes recent advances in our understanding of the transcriptional mechanisms that control brown and beige fat cell development.
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