4.6 Review

A Decade of Antifungal Leads from Natural Products: 2010-2019

Journal

PHARMACEUTICALS
Volume 12, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/ph12040182

Keywords

fungal pathogens; antifungal agents; natural products

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In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.

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