4.2 Article

Atypical presentations of MERS-CoV infection in immunocompromised hosts

Journal

JOURNAL OF INFECTION AND CHEMOTHERAPY
Volume 23, Issue 11, Pages 769-773

Publisher

ELSEVIER
DOI: 10.1016/j.jiac.2017.04.004

Keywords

Middle East respiratory syndrome coronavirus; Immunocompromised host; Incubation period; Asymptomatic period; Corticosteroid

Funding

  1. Samsung Biomedical Research Institute (SBRI) grant [SMX1161321]

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During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks. (C) 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

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