Synthesis and Antibacterial Activity Studies of 8,9-Dihydro [7h] Benzo 1,2,4-Oxadiazoles and its Coumarin Derivatives

Synthesis, characterization, and antibacterial active studies of 12 coumarin derivatives were described in this study. Synthesis was achieved by the reaction of 4-carbonyl chloride with 1,2-dichloroethane as a solvent, in moderate to good yields. The structures of all the newly synthesized molecules were assigned by spectral data and elemental analysis. The synthesized compounds were screened for their antibacterial activities strains using paper disc method.