4.7 Editorial Material

Myelination: Actin Disassembly Leads the Way

Journal

DEVELOPMENTAL CELL
Volume 34, Issue 2, Pages 129-130

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2015.07.006

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Funding

  1. NINDS NIH HHS [R01 NS026001] Funding Source: Medline

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The mechanisms that drive the spiral wrapping of the myelin sheath around axons are poorly understood. Two papers in this issue of Developmental Cell demonstrate that actin disassembly, rather than actin assembly, predominates during oligodendrocyte maturation and is critical for the genesis of the central myelin sheath.

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