Importance of Detoxification Processes in Ozone Risk Assessment: Need to Integrate the Cellular Compartmentation of Antioxidants?

The correct integration of the detoxification processes in a risk assessment model for ozone damage on plants remains challenging. In particular, the intracellular compartmentation of antioxidant metabolites could play a role, since each compartment presents its own sensitivity to ROS and metabolite set. For each compartment, we tried to provide both qualitative and quantitative information on the metabolites present as well as the putative transporters implied. When they are known, the modifications caused by O-3 or oxidative stress are presented. Clearly, under O-3 exposure, integrative data which would allow to improve predictive models for O-3 risk assessment are missing.