Journal
JOURNAL OF HEPATOLOGY
Volume 67, Issue 5, Pages 1084-1103Publisher
ELSEVIER
DOI: 10.1016/j.jhep.2017.05.007
Keywords
Gut-liver-axis; Bacterial translocation; Liver injury; Fibrosis; Cirrhosis; Bile acids; Microbiome; Incretines; Pre-, probiotics; Faecal microbial transplantation
Categories
Funding
- European Union's Horizon research and innovation programme [634579]
- Swiss National Fund [SNF 17-231]
- H2020 Societal Challenges Programme [634579] Funding Source: H2020 Societal Challenges Programme
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The gut-liver axis is widely implicated in the pathogenesis of liver diseases, where it is increasingly the focus of clinical research. Recent studies trialling an array of therapeutic and preventative strategies have yielded promising results. Considering these strategies, the armamentarium for targeting the gut-liver axis will continue to expand. Further clinical trials, translated from our current knowledge of the gut-liver axis, promise an exciting future in liver treatment. (C) 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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