4.3 Review

Nanoparticle-membrane interactions

Journal

JOURNAL OF EXPERIMENTAL NANOSCIENCE
Volume 13, Issue 1, Pages 62-81

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/17458080.2017.1413253

Keywords

nanotoxicity; nanomaterial; membrane interface; nanoparticle

Funding

  1. European Union's Horizon 2020 research and innovation programme (Smartnanotox project) [686098]

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Engineered nanomaterials have a wide range of applications and as a result, are increasingly present in the environment. While they offer new technological opportunities, there is also the potential for adverse impact, in particular through possible toxicity. In this review, we discuss the current state of the art in the experimental characterisation of nanoparticle-membrane interactions relevant to the prediction of toxicity arising from disruption of biological systems. One key point of discussion is the urgent need for more quantitative studies of nano-bio interactions in experimental models of lipid system that mimic in vivo membranes.

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