3.8 Proceedings Paper

Generative Adversarial Networks as an Advanced Data Augmentation Technique for MRI Data

Publisher

SCITEPRESS
DOI: 10.5220/0007363900480059

Keywords

Generative Adversarial Networks; Deep Learning; MRI; Data Augmentation; ADNI; Alzheimer's Disease

Funding

  1. Alzheimer's Disease Neuroimaging Initiative (ADNI) (National Institutes of Health) [U01 AG024904]
  2. DOD ADNI (Department of Defense) [W81XWH-12-2-0012]
  3. National Institute on Aging
  4. National Institute of Biomedical Imaging and Bioengineering
  5. AbbVie
  6. Alzheimer's Association
  7. Alzheimer's Drug Discovery Foundation
  8. Araclon Biotech
  9. BioClinica, Inc.
  10. Biogen
  11. Bristol-Myers Squibb Company
  12. CereSpir, Inc.
  13. Cogstate
  14. Eisai Inc.
  15. Elan Pharmaceuticals, Inc.
  16. Eli Lilly and Company
  17. EuroImmun
  18. F. Hoffmann-La Roche Ltd and its affiliated company Genentech, Inc.
  19. Fujirebio
  20. GE Healthcare
  21. IXICO Ltd.
  22. Janssen Alzheimer Immunotherapy Research & Development, LLC.
  23. Johnson & Johnson Pharmaceutical Research & Development LLC.
  24. Lumosity
  25. Lundbeck
  26. Merck Co., Inc.
  27. Meso Scale Diagnostics, LLC.
  28. NeuroRx Research
  29. Neurotrack Technologies
  30. Novartis Pharmaceuticals Corporation
  31. Pfizer Inc.
  32. Piramal Imaging
  33. Servier
  34. Takeda Pharmaceutical Company
  35. Transition Therapeutics
  36. The Canadian Institutes of Health Research

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This paper presents a new methodology for data augmentation through the use of Generative Adversarial Networks. Traditional augmentation strategies are severely limited, especially in tasks where the images follow strict standards, as is the case in medical datasets. Experiments conducted on the ADNI dataset prove that augmentation through GANs outperforms traditional methods by a large margin, based both on the validation accuracy and the models' generalization capability on a holdout test set. Although traditional data augmentation did not seem to aid the classification process in any way, by adding GAN-based augmentation an increase of 11.68% in accuracy was achieved. Furthermore, by combining traditional with GAN-based augmentation schemes, even higher accuracies can be reached.

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