Journal
CHEMICAL PAPERS
Volume 74, Issue 4, Pages 1071-1078Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s11696-019-00946-z
Keywords
Benzothiazole salts; Triphenylamine; Viscosity; Mitochondrial; Mitochondrial membrane potential
Categories
Funding
- Anhui Provincial Natural Science Foundation [1908085QB50]
- Doctoral Startup Foundation of Wannan Medical College [wYRCQD201715]
- Young Foundation of Wannan Medical College [WK201807]
- Natural Science Fund of Education Department of Anhui province [KJ2018A0257]
- Scientific Research Foundation for Academic and Technical Leader Reserve Candidate of Anhui Province [2016H086]
Ask authors/readers for more resources
In this paper, we developed a red-emitting fluorescent probe TPSN based on triphenylamine-functionalized benzothiazole salts. TPSN exhibits a strong luminescence emission at about 637 nm in viscous media. Moreover, the fluorescence intensity of TPSN enhances approximately 94-fold from water to 99% glycerol. Cell imaging experiments reveals that TPSN presents high specificity for mitochondrial localization. The related mechanism study indicates that the localization property of TPSN is independent of the mitochondrial membrane potential. As a result, TPSN offers a promising tool to monitor the mitochondria viscosity in living cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
