4.7 Article

Cobalt-based metal organic frameworks: a highly active oxidase-mimicking nanozyme for fluorescence turn-on assays of biothiol

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 4, Pages 659-662

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc06840f

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Funding

  1. Natural National Science Foundation of China [21673022]
  2. Fundamental Research Funds for the Central Universities

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Co-based metal organic frameworks (ZIF-67), working as an oxidase-mimicking nanozyme, can simultaneously catalyze the oxidation of 3,3 ',5,5 '-tetramethylbenzidine, 2,2 '-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) and Amplex red, exhibiting a high catalytic activity. For Amplex red, two consecutive redox reactions are reported, which is specifically applied for fluorescence turn-on detection of biothiols.

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