Journal
NANOSCALE
Volume 12, Issue 4, Pages 2328-2332Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9nr08467c
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Funding
- National Health & Medical Research Council of Australia (NHMRC) Early Career Fellowship
- Australian Microscopy and Microanalysis Research Facility at the Centre for Microscopy and Microanalysis, the University of Queensland
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Deoxyribonuclease I (DNase I) was successfully loaded and delivered by silver-doped mesoporous silica nanoparticles (MSN-Ag) for biofilm treatments. This nanoformulation showed enhanced antibacterial effects for both Gram-negative and Gram-positive biofilms by promoting the biofilm biomass dispersing ability of DNase I.
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