4.7 Article

Bright carbon dots as fluorescence sensing agents for bacteria and curcumin

Journal

JOURNAL OF COLLOID AND INTERFACE SCIENCE
Volume 501, Issue -, Pages 341-349

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jcis.2017.04.045

Keywords

Carbon dots; Fluorescence; Bacteria; Curcumin; Forster resonance energy transfer (FRET)

Funding

  1. Ministry of Science and Technology of Taiwan [MOST102-2113-M-009-019-MY3]
  2. NCTU

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Carbon dots (C-dots) are fluorescent nanomaterials that possess good photostability and low toxicity. They have been used as sensing probes and bioimaging agents for a variety of biological species. Numerous methods are available to generate C-dots. Nevertheless, simple and straightforward synthesis methods must be explored for the synthesis of C-dots from inexpensive, natural sources. In this study, we developed a simple method to generate C-dots from inexpensive chicken egg whites through a one-step heating reaction. The size of the generated C-dots was 3.3 +/- 0.4 nm, and the quantum yield of the C-dots was as high as similar to 43%. The as-prepared C-dots can be used as multicolor labeling agents for bacteria such as Staphylococcus aureus and Escherichia coli. Furthermore, the generated C-dots can be used as Forster resonance energy transfer sensing probes for curcumin, which is an active ingredient of turmeric and medicinal pigment. The feasibility of using the C-dots as selective sensing probes to determine the amount of curcumin from complex turmeric powder and condensed turmeric tablets is also demonstrated. (C) 2017 Elsevier Inc. All rights reserved.

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