4.7 Article

Visualization of the cysteine level during Golgi stress using a novel Golgi-targeting highly specific fluorescent probe

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 12, Pages 1807-1810

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc08796f

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Funding

  1. National Natural Science Foundation of China [21607053, 21777053]
  2. Shandong Provincial Natural Science Foundation [ZR2017MB014, ZR2018PC013]
  3. project of the Shandong Province Higher Educational Science and Technology Support Program for Young Innovation [2019KJD005]

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A novel Golgi-targeting Cys-specific fluorescent probe (Gol-Cys) was synthesized. Probe Gol-Cys is not only sufficiently sensitive to native Cys in living cells and zebrafish, but also can be used for monitoring the Cys level during Golgi stress.

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