Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 55, Issue 10, Pages 2884-2893Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00489-17
Keywords
immunocompromised hosts; transplantation; virome
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Funding
- National Institutes of Health (NIH) [5T32AI007502-20]
- Stanford Translational Research and Applied Medicine (TRAM) Pilot Grant Program
- TL1 Clinical Research Training Program of the Stanford Clinical and Translational Science Award to Spectrum [TL1 TR 001084]
- NIH/NIAID [U19AI109761]
- Thomas C. and Joan M. Merigan Endowment at Stanford University
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Advances in DNA sequencing technology have provided an unprecedented opportunity to study the human virome. Transplant recipients and other immunocom-promised hosts are at particular risk for developing virus-related pathology; thus, the impact of the virome on health and disease may be even more relevant in this population. Here, we discuss technical considerations in studying the human virome, the current literature on the virome in transplant recipients, and near-future applications of sequence-based findings that can further our understanding of viruses in transplantation medicine.
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