4.7 Article

A facile analytical method for reliable selectivity examination in cofactor NADH regeneration

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 8, Pages 1231-1234

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc07805c

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Funding

  1. Royal Society [ICA\R1\180317, IES\R3\170162]

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This study demonstrates a novel method to quantify selective (1,4-NADH) and unselective products (1,2- and 1,6-NADH) in NADH regeneration using combined UV-Vis spectroscopy and biological assays. The validity of the proposed method was tested in the Pt/C promoted NAD(+) hydrogenation using hydrogen as reducing agent.

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