Manganese and selenium concentrations in cerebrospinal fluid of seriously ill children

BackgroundThe homeostasis of essential trace elements such as selenium and manganese may be altered in patients with severe diseases of various etiologies (trauma brain injuries, tumors, leukemias, lymphomas, neurological diseases). MethodsConcentration of manganese and selenium were determined in cerebrospinal fluid by electrothermal atomic absorption spectrometry in 50 hospitalized children with various clinical ethiologies including oncological, neurological, and brain related diseases. ResultsThe concentrations of manganese in cerebrospinal fluid of children were 0.970.67g/L. The concentrations of selenium were 13.3 +/- 3.5g/L. The concentrations were similar as published in adults. The values did not correlated with the age, gender and severity of the disease. ConclusionWe evaluated values of selenium and manganese in cerebrospinal fluid of seriously diseased children.