Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 7, Issue 3, Pages 578-583Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9qo01402k
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21871113, 21773214, 21372101]
- Priority Academic Program Development of Jiangsu Higher Education Institution
- TAPP
Ask authors/readers for more resources
NHC-catalyzed desulfonylation of tosylated aldimines provides facile access to aryl nitriles in generally good to excellent yields with good functional group compatibilities under mild reaction conditions. DFT calculations demonstrate that the reaction undergoes multiple stepwise processes including nucleophilic addition of NHC to tosylated imine, formation of an aza-Breslow intermediate, deprotonation, and dissociation of the tosyl group.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available