4.7 Article

Visible-light-promoted acridine red catalyzed aerobic oxidative decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones

Journal

ORGANIC CHEMISTRY FRONTIERS
Volume 7, Issue 3, Pages 492-498

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9qo01334b

Keywords

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Funding

  1. Youth Innovation and Technology Project of Shandong Province [2019KJC021]
  2. Natural Science Foundation of Shandong Province [ZR2018MB009]
  3. International Cooperation Project of Qinghai Province [2018-HZ-806]
  4. Qinghai Key Laboratory of Tibetan Medicine Research [2017-ZJ-Y11]
  5. National Natural Science Foundation of China [31900298, 21302109]

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A mild and facile visible-light-mediated strategy has been proposed for the synthesis of 3-acyl quinoxalin-2(1H)-ones through acridine red catalyzed aerobic oxidative decarboxylative acylation of alpha-oxo-carboxylic acids with quinoxalin-2(1H)-ones at room temperature in air. Various 3-acyl quinoxalin-2(1H)-ones could be efficiently obtained in good yields with excellent functional group compatibility.

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