Journal
JOURNAL OF CLINICAL GASTROENTEROLOGY
Volume 52, Issue 3, Pages 204-209Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCG.0000000000000965
Keywords
sleep dysfunction; intestinal homeostasis; intestinal dysbiosis; intermittent hypoxia
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Sleep dysfunction is an epidemic, the implications of which have a profound impact on a variety of gastrointestinal disease. Recent data suggests a relationship between sleep dysfunction and intestinal dysbiosis, a known proinflammatory driver. This article evaluates the interplay between sleep dysfunction and gastrointestinal health and disease, with a focus on the impact of circadian rhythm disruption on the commensal microbiota.
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