Journal
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
Volume 93, Issue 4, Pages 1031-1043Publisher
WILEY
DOI: 10.1002/jctb.5456
Keywords
sugarcane bagasse cellulignin; enzymatic hydrolysis; acid pretreatment; artificial neural network; glucose yield
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Funding
- FAPESP [2012/10857-3, 2016/01785-0]
- BIOEN/FAPESP Bioenergy Research Program [2008/57873-8]
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BACKGROUND: In this work a single artificial neural network (ANN) was used to model the overall yield of glucose (Y-GLC) as a function of a wide range of operating conditions of both pretreatment and enzymatic hydrolysis. RESULTS: The model was validated experimentally and presented good predictions of Y-GLC. Sensitivity analysis using the ANN model indicated that most of the operating parameters, except for pretreatment time, were statistically significant (P-value<0.05). Experiments showed that the processing of sugarcane bagasse (in natura) results in a satisfactory glucose yield of 69.34% when pretreated for 60 min with low initial biomass concentration and acid concentration (10% and 1.0% w/v), and followed by enzymatic hydrolysis for 72 h with 3.0% w/v substrate loading and 60 FPU per g(WIS) enzyme concentration. CONCLUSION: This study demonstrated how pretreatment and enzymatic hydrolysis data can be used to parameterize a single ANN model. Acceptable predictions of Y-GLC are achieved in terms of RSD, MSE and R-2. Supported by the model, this study provided a good insight for process development. (C) 2017 Society of Chemical Industry.
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