Related references
Note: Only part of the references are listed.Defects in mitochondrial energetic function compels Fanconi Anaemia cells to glycolytic metabolism
Enrico Cappelli et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice
Qing-Shuo Zhang et al.
BLOOD (2016)
Why is an energy metabolic defect the common outcome in BMFS?
Paolo Degan et al.
CELL CYCLE (2016)
Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity
Trillian Gregg et al.
DIABETES (2016)
Metformin From Research to Clinical Practice
Meng H. Tan et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2016)
Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial
Takuma Higurashi et al.
LANCET ONCOLOGY (2016)
Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine
Himalee S. Sabins et al.
LEUKEMIA RESEARCH (2016)
Metformin-induced protection against oxidative stress is associated with AKT/mTOR restoration in PC12 cells
Behzad Khallaghi et al.
LIFE SCIENCES (2016)
Sirt1 and the Mitochondria
Bor Luen Tang
MOLECULES AND CELLS (2016)
The radioprotective effect of metformin against cytotoxicity and genotoxicity induced by ionizing radiation in cultured human blood lymphocytes
Mohsen Cheki et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2016)
Repurposing metformin for cancer treatment: current clinical studies
Young Kwang Chae et al.
ONCOTARGET (2016)
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
Masahiro Morita et al.
CELL CYCLE (2015)
Metformin Action: Concentrations Matter
Ling He et al.
CELL METABOLISM (2015)
Effects of metformin on mitochondrial function of leukocytes from polycystic ovary syndrome patients with insulin resistance
Victor M. Victor et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2015)
Oxidative stress in myelin sheath: The other face of the extramitochondrial oxidative phosphorylation ability
S. Ravera et al.
FREE RADICAL RESEARCH (2015)
Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium
Mustafa Kinaan et al.
MEDICAL PRINCIPLES AND PRACTICE (2015)
Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
Giovanna Bianchi et al.
ONCOTARGET (2015)
AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis
B. Chaube et al.
CELL DEATH DISCOVERY (2015)
AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease
D. Grahame Hardie
JOURNAL OF INTERNAL MEDICINE (2014)
Metformin inhibits-the growth-of nasopharyngeal carcinoma cells and sensitizes the cells to radiation via inhibition of the DNA damage repair pathway
Haiwen Li et al.
ONCOLOGY REPORTS (2014)
Treatment of FANCA Cells with Resveratrol and N-Acetylcysteine: A Comparative Study
Marta Columbaro et al.
PLOS ONE (2014)
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton et al.
ELIFE (2014)
Metformin directly acts on mitochondria to alter cellular bioenergetics
Sylvia Andrzejewski et al.
CANCER & METABOLISM (2014)
Mitochondrial respiratory chain Complex I defects in Fanconi anemia complementation group A
Silvia Ravera et al.
BIOCHIMIE (2013)
mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
Masahiro Morita et al.
CELL METABOLISM (2013)
Mitochondrial Dynamics - Mitochondrial Fission and Fusion in Human Diseases
Stephen L. Archer
NEW ENGLAND JOURNAL OF MEDICINE (2013)
mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology
Charles Betz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mitochondrial respiratory complex I defects in Fanconi anemia
Enrico Cappelli et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Metformin in obesity, cancer and aging: addressing controversies
Lev M. Berstein
AGING-US (2012)
A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells
Lauren E. Nelson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
Fanconi Anemia Links Reactive Oxygen Species to Insulin Resistance and Obesity
Jie Li et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Cellular and molecular mechanisms of metformin: an overview
Benoit Viollet et al.
CLINICAL SCIENCE (2012)
Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration
S. Larsen et al.
DIABETOLOGIA (2012)
New insights into redox response modulation in Fanconi's anemia cells by hydrogen peroxide and glutathione depletors
Paola Cuccarolo et al.
FEBS JOURNAL (2012)
Clinical Pharmacokinetics of Metformin
Garry G. Graham et al.
CLINICAL PHARMACOKINETICS (2011)
Metformin in polycystic ovary syndrome
Evanthia Diamanti-Kandarakis et al.
WOMEN'S HEALTH AND DISEASE (2010)
Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway
Xinguo Hou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats
Daniel A. Kane et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Influence of metformin on GLUT1 gene and protein expression in rat streptozotocindiabetes mellitusmodel
Jelizaveta Sokolovska et al.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2010)
The genetic and molecular basis of Fanconi anemia
Johan P. de Winter et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2009)
Abnormalities in glucose tolerance are common in children with Fanconi Anemia and associated with impaired insulin secretion
Deborah A. Elder et al.
PEDIATRIC BLOOD & CANCER (2008)
Activation of AMP-activated protein kinase reduces hyperglycemia-Induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
D Kukidome et al.
DIABETES (2006)
Metformin enhances insulin signalling in insulin-dependent and -independent pathways in insulin resistant muscle cells
N Kumar et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool
H Hanenberg et al.
EXPERIMENTAL HEMATOLOGY (2002)
Mitochondrial free radical generation, oxidative stress, and aging
E Cadenas et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)