4.7 Editorial Material

Ragulator - a multifaceted regulator of lysosomal signaling and trafficking

Journal

JOURNAL OF CELL BIOLOGY
Volume 216, Issue 12, Pages 3895-3898

Publisher

ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201710039

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Funding

  1. European Research Council [AdG 340751]
  2. Danish National Research Foundation [DNRF125]
  3. Danish Cancer Society [R90-A5783]
  4. Novo Nordisk Foundation [NNF15OC0016914]
  5. Novo Nordisk Fonden [NNF15OC0016914] Funding Source: researchfish
  6. The Danish Cancer Society [R90-A5783] Funding Source: researchfish

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The lysosomal Ragulator complex regulates cell metabolism and growth by coordinating the activities of metabolic signaling pathways with nutrient availability. In this issue, Filipek et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703061) and Pu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703094) introduce a role for Ragulator in growth factor- and nutrient-regulated lysosomal trafficking.

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