Journal
JOURNAL OF PEDIATRIC SURGERY CASE REPORTS
Volume 54, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.epsc.2019.101374
Keywords
Empyema; Tissue plasminogen activator (tPA); Pleural effusion
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Empyema is an infection of the pleural space, often secondary to pneumonia. Although frequently encountered in pediatric surgical practice, it is rarely encountered in neonatal patients, and little data exists to guide treatment of neonatal empyema. One strategy is to extrapolate from pediatric treatment paradigms, specifically involving the use of intrapleural fibrinolytic therapy. Herein, we report on a rare case of neonatal empyema successfully treated using tissue plasminogen activator (tPA) via chest tube at a dose of 0.1 mg/kg in 5 mL normal saline daily for 3 days.
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