4.7 Article

Imaging endogenous HClO in atherosclerosis using a novel fast-response fluorescence probe

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 17, Pages 2598-2601

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc07256j

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Funding

  1. National Key Research and Development Program of China [2017YFC1601704]

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A novel pyrene-based naked-eye colorimetric and fluorescent turn-on probe (S-ClO) was developed. Besides, imaging in living RAW264.7 cells, an arterial vessel inflammation nude mouse model and human serum using S-ClO indicates that S-ClO could serve as a potential tool for early diagnosing and monitoring inflammatory diseases.

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