Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 16, Pages 2411-2414Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc08858j
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Herein, polymerization-induced electrostatic self-assembly (PIESA) is conducted to mediate the self-assembly behavior of short interfering RNA (siRNA) for the first time. In PIESA, siRNA not only formed a simple electrostatic polyplex with positively charged polycations, but also facilitated directed self-assembly due to the molecular rigidity of siRNA, leading to appealing nanotubes.
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