Journal
RSC ADVANCES
Volume 10, Issue 15, Pages 8586-8593Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ra01043j
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Funding
- National Natural Science Foundation of China [21572162]
- Natural Science Foundation of Zhejiang Province [LY20B020015]
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The first example of the palladium-catalyzed cascade reaction of o-aminocinnamonitriles with arylhydrazines has been achieved, providing an efficient synthetic pathway to access quinolines with moderate to good yields. Preliminary mechanistic experiments indicate that this cascade process involves sequential denitrogenative addition followed by an intramolecular cyclization.
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