Journal
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
Volume 106, Issue 5, Pages 1637-1644Publisher
WILEY
DOI: 10.1002/jbm.b.34012
Keywords
biocompatible pristine carbon nanotube substrate; pancreatic adenocarcinoma; pancreatic cancer tissue engineering; extracellular matrix
Funding
- Surrey Impact Acceleration Awards (IAA) [2015/KN9149C, 2015/K031562/1 + G060878]
- EPSRC-IAA [2016/RN0281J]
- EPSRC [EP/K031562]
- Royal Society [2016/RA4030]
- Ministry of Education and Science of the Russian Federation [14.Y26.31.0010]
- Increase Competitiveness Program of NUST MISiS [K2-2015-014]
- Welch Foundation [AT 16-17]
- Engineering and Physical Sciences Research Council [EP/K031562/1] Funding Source: researchfish
- EPSRC [EP/K031562/1] Funding Source: UKRI
Ask authors/readers for more resources
Novel synthetic biomaterials able to support direct tissue growth and retain cellular phenotypical properties are promising building blocks for the development of tissue engineering platforms for accurate and fast therapy screening for cancer. The aim of this study is to validate an aligned, pristine multi-walled carbon nanotube (CNT) platform for in vitro studies of pancreatic cancer as a systematic understanding of interactions between cells and these CNT substrates is lacking. Our results demonstrate that our CNT scaffoldswhich are easily tuneable to form sheets/fiberssupport growth, proliferation, and spatial organization of pancreatic cancer cells, indicating their great potential in cancer tissue engineering. (c) 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1637-1644, 2018.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
