Journal
ACTAS DERMO-SIFILIOGRAFICAS
Volume 111, Issue 1, Pages 20-25Publisher
ELSEVIER ESPANA
DOI: 10.1016/j.ad.2019.02.010
Keywords
Spitz nevus; Spitzoid tumors; Atypical Spitz tumor; Spitzoid melanoma
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Melanocytic neoplasms with spitzoid morphology (Spitz nevi, atypical Spitz tumors, and spitzoid melanomas) may be benign or malignant. Because the malignant potential of atypical Spitz tumors is uncertain, the proper therapeutic approach has been much debated over the years. Promising new techniques for molecular analysis have enabled better predictions of the biological behavior of these tumors. We review their cytogenetic features and prognosis and also provide an update of the most recent recommendations for management. (C) 2020 Published by Elsevier Espana, S.L.U. on behalf of AEDV.
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