Related references
Note: Only part of the references are listed.TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice
Anne K. McGavigan et al.
GUT (2017)
G-Protein-Coupled Bile Acid Receptor Plays a Key Role in Bile Acid Metabolism and Fasting-Induced Hepatic Steatosis in Mice
Ajay C. Donepudi et al.
HEPATOLOGY (2017)
Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice
Yang Xu et al.
HEPATOLOGY (2016)
Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans
Shogo Takahashi et al.
JOURNAL OF LIPID RESEARCH (2016)
Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid
Gideon M. Hirschfield et al.
GASTROENTEROLOGY (2015)
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
Brent A. Neuschwander-Tetri et al.
LANCET (2015)
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
Sungsoon Fang et al.
NATURE MEDICINE (2015)
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells
Mohamed-Sami Trabelsi et al.
NATURE COMMUNICATIONS (2015)
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
Changtao Jiang et al.
NATURE COMMUNICATIONS (2015)
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease
Changtao Jiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
FXR is a molecular target for the effects of vertical sleeve gastrectomy
Karen K. Ryan et al.
NATURE (2014)
Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Protects Mice against Atherosclerosis
Shinobu Miyazaki-Anzai et al.
PLOS ONE (2014)
Bile Acid Signaling in Metabolic Disease and Drug Therapy
Tiangang Li et al.
PHARMACOLOGICAL REVIEWS (2014)
Human Insulin Resistance Is Associated With Increased Plasma Levels of 12a-Hydroxylated Bile Acids
Rebecca A. Haeusler et al.
DIABETES (2013)
Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease
Rachel H. McMahan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
Fei Li et al.
NATURE COMMUNICATIONS (2013)
Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
H. E. Parker et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Bile Acids Acutely Stimulate Insulin Secretion of Mouse β-Cells via Farnesoid X Receptor Activation and KATP Channel Inhibition
Martina Duefer et al.
DIABETES (2012)
Glucose and Insulin Induction of Bile Acid Synthesis MECHANISMS AND IMPLICATION IN DIABETES AND OBESITY
Tiangang Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Conjugated Bile Acids Associate with Altered Rates of Glucose and Lipid Oxidation after Roux-en-Y Gastric Bypass
M. Simonen et al.
OBESITY SURGERY (2012)
TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
Taoufiq Harach et al.
SCIENTIFIC REPORTS (2012)
Dual Farnesoid X Receptor/TGR5 Agonist INT-767 Reduces Liver Injury in the Mdr2-/- (Abcb4-/-) Mouse Cholangiopathy Model by Promoting Biliary HCO3- Output
Anna Baghdasaryan et al.
HEPATOLOGY (2011)
Nuclear Receptors in Liver Disease
Martin Wagner et al.
HEPATOLOGY (2011)
The bile acid sensor FXR regulates insulin transcription and secretion
Barbara Renga et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Transgenic Expression of Cholesterol 7α-Hydroxylase in the Liver Prevents High-Fat Diet Induced Obesity and Insulin Resistance in Mice
Tiangang Li et al.
HEPATOLOGY (2010)
Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
Giovanni Rizzo et al.
MOLECULAR PHARMACOLOGY (2010)
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
Charles Thomas et al.
CELL METABOLISM (2009)
Bile acids: regulation of synthesis
John Y. L. Chiang
JOURNAL OF LIPID RESEARCH (2009)
Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism
Mary-Elizabeth Patti et al.
OBESITY (2009)
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Philippe Lefebvre et al.
PHYSIOLOGICAL REVIEWS (2009)
Expression and function of the bile acid receptor TGR5 in Kupffer cells
Verena Keitel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
A novel role of transforming growth factor β1 in transcriptional repression of human cholesterol 7α-hydroxylase gene
Tiangang Li et al.
GASTROENTEROLOGY (2007)
Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
Galya Vassileva et al.
BIOCHEMICAL JOURNAL (2006)
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
M Watanabe et al.
NATURE (2006)
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
T Inagaki et al.
CELL METABOLISM (2005)
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
S Katsuma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
M Watanabe et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of membrane-type receptor for bile acids (M-BAR)
T Maruyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
CJ Sinal et al.
CELL (2000)
Share Paper
