4.6 Article

High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

NMR based model of human telomeric repeat G-quadruplex in complex with 2,4,6-triarylpyridine family ligand

Abdelaziz Kerkour et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)

Article Biochemistry & Molecular Biology

Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes

Josue Carvalho et al.

BIOCHIMIE (2017)

Article Biochemistry & Molecular Biology

An intramolecular G-quadruplex structure formed in the human MET promoter region and its biological relevance

Jing Yan et al.

MOLECULAR CARCINOGENESIS (2016)

Article Biochemistry & Molecular Biology

KRAS promoter oligonucleotide with decoy activity dimerizes into a unique topology consisting of two G-quadruplex units

Peter Podbevsek et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Biochemistry & Molecular Biology

G4 DNA in ras genes and its potential in cancer therapy

Susanna Cogoi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2016)

Review Genetics & Heredity

K-Ras protein as a drug target

Frank McCormick

JOURNAL OF MOLECULAR MEDICINE-JMM (2016)

Article Biochemistry & Molecular Biology

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

Jutta Zimmer et al.

MOLECULAR CELL (2016)

Article Biochemistry & Molecular Biology

G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV

Advaitha Madireddy et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

G-quadruplexes as novel cis-elements controlling transcription during embryonic development

Aldana P. David et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome

Beatrice De Nicola et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Re-evaluation of G-quadruplex propensity with G4Hunter

Amina Bedrat et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Genetics & Heredity

G-Quadruplexes in DNA Replication: A Problem or a Necessity?

Anne-Laure Valton et al.

TRENDS IN GENETICS (2016)

Article Multidisciplinary Sciences

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

Philipp M. Cromm et al.

NATURE COMMUNICATIONS (2016)

Article Chemistry, Medicinal

Multivalent LKγ-PNA oligomers bind to a human telomere DNA G-rich sequence to form quadruplexes

Pankaj Gupta et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)

Article Biochemistry & Molecular Biology

In-silico modeling studies of G-quadruplex with soy isoflavones having anticancerous activity

Jyoti Singh Tomar

JOURNAL OF MOLECULAR MODELING (2015)

Article Biotechnology & Applied Microbiology

High-throughput sequencing of DNA G-quadruplex structures in the human genome

Vicki S. Chambers et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes

Matjaz Boncina et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

Elizaveta S. Leshchiner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines

Joao Lavrado et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

U3 Region in the HIV-1 Genome Adopts a G-Quadruplex Structure in Its RNA and DNA Sequence

Dorota Piekna-Przybylska et al.

BIOCHEMISTRY (2014)

Review Oncology

Oncogenic KRAS signalling in pancreatic cancer

S. Eser et al.

BRITISH JOURNAL OF CANCER (2014)

Article Chemistry, Multidisciplinary

A Twice-As-Smart Synthetic G-Quartet: PyroTASQ Is Both a Smart Quadruplex Ligand and a Smart Fluorescent Probe

Aurelien Laguerre et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Review Biotechnology & Applied Microbiology

Drugging the undruggable RAS: Mission Possible?

Adrienne D. Cox et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Biochemistry & Molecular Biology

Mechanistic insight into ligand binding to G-quadruplex DNA

Francesco Saverio Di Leva et al.

NUCLEIC ACIDS RESEARCH (2014)

Review Pharmacology & Pharmacy

Targeting pathways downstream of KRAS in lung adenocarcinoma

Zehua Zhu et al.

PHARMACOGENOMICS (2014)

Editorial Material Oncology

Multi-kinase modulation for colon cancer therapy

Paul Dent

CANCER BIOLOGY & THERAPY (2013)

Article Chemistry, Multidisciplinary

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

Vineeth Thachappilly Mukundan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Multidisciplinary Sciences

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

Jonathan M. Ostrem et al.

NATURE (2013)

Article Pathology

Antisense Knockdown of Kras Inhibits Fibrosis in a Rat Model of Unilateral Ureteric Obstruction

Jia-Hui Wang et al.

AMERICAN JOURNAL OF PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying et al.

Review Pharmacology & Pharmacy

G-quadruplexes: targets and tools in anticancer drug design

Markus Duechler

JOURNAL OF DRUG TARGETING (2012)

Article Biochemistry & Molecular Biology

Interaction of human telomeric DNA with N-methyl mesoporphyrin IX

John M. Nicoludis et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemistry & Molecular Biology

Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops

Maja Marusic et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Chemistry, Multidisciplinary

Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE

Manikandan Paramasivam et al.

CHEMICAL COMMUNICATIONS (2011)

Article Biochemistry & Molecular Biology

G-quadruplex-induced instability during leading-strand replication

Judith Lopes et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Simon A. Forbes et al.

NUCLEIC ACIDS RESEARCH (2011)

Review Oncology

Targeting protein prenylation for cancer therapy

Norbert Berndt et al.

NATURE REVIEWS CANCER (2011)

Article Chemistry, Multidisciplinary

Rapid Stoichiometric Analysis of G-Quadruplexes in Solution

Patrick Groves et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

Review Pharmacology & Pharmacy

Therapeutic modulation of k-ras signaling in colorectal cancer

Lisanne L. Krens et al.

DRUG DISCOVERY TODAY (2010)

Review Biochemistry & Molecular Biology

Human telomeric G-quadruplex: structures of DNA and RNA sequences

Anh Tuan Phan

FEBS JOURNAL (2010)

Article Biochemistry & Molecular Biology

How long is too long? Effects of loop size on G-quadruplex stability

Aurore Guedin et al.

NUCLEIC ACIDS RESEARCH (2010)

Review Biochemistry & Molecular Biology

A Toolbox for Predicting G-Quadruplex Formation and Stability

Han Min Wong et al.

JOURNAL OF NUCLEIC ACIDS (2010)

Article Biochemical Research Methods

Predicting and understanding the stability of G-quadruplexes

Oliver Stegle et al.

BIOINFORMATICS (2009)

Review Biochemistry & Molecular Biology

G-quadruplex nucleic acids as therapeutic targets

Shankar Balasubramanian et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

E. coli Transports Aggregated Proteins to the Poles by a Specific and Energy-Dependent Process

Assaf Rokney et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Chemistry, Multidisciplinary

A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics

Shang-Te Danny Hsu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Biochemistry & Molecular Biology

Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

Manikandan Paramasivam et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Biochemistry & Molecular Biology

Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

Anh Tuan Phan et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Chemistry, Multidisciplinary

Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter

Anh Tuan Phan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Biochemistry & Molecular Biology

Enrichment of G4 DNA motif in transcriptional regulatory region of chicken genome

Zhuo Du et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Biochemical Research Methods

Version 1.2 of the Crystallography and NMR system

Axel T. Brunger

NATURE PROTOCOLS (2007)

Article Biochemistry & Molecular Biology

G-quadruplexes in promoters throughout the human genome

Julian L. Huppert et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Biochemistry & Molecular Biology

Gene function correlates with potential for G4 DNA formation in the human genome

Johanna Eddy et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription

Susanna Cogoi et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

AT Phan et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Highly prevalent putative quadruplex sequence motifs in human DNA

AK Todd et al.

NUCLEIC ACIDS RESEARCH (2005)

Article Biochemistry & Molecular Biology

Prevalence of quadruplexes in the human genome

JL Huppert et al.

NUCLEIC ACIDS RESEARCH (2005)

Article Chemistry, Multidisciplinary

Propeller-type parallel-stranded g-quadruplexes in the human c-myc promoter

AT Phan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Gastroenterology & Hepatology

Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma

HJN Andreyev et al.