Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 20, Issue 3, Pages 242-248Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2017.1323884
Keywords
Verbenacase; Callicarpa nudiflora; iridoid glycosides; hepatoprotective activity
Funding
- National Natural Science Foundation of China [NSFC] [81373955, 81460589]
- Natural Science Foundation of Jiangxi, China [20142BAB205085]
- Fund for the Development of Youth in Inspection Institute of Research [2013WA9]
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Two new iridoid glycosides, callicoside C (1) and callicoside D (2), together with three known compounds (3-5), were isolated from the leaves of Callicarpa nudiflora. Their structures were established by 1D and 2D NMR spectroscopy and mass spectrometry. In an in vitro bioassay, compound 1 showed pronounced hepatoprotective activity against d-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells. [GRAPHICS] .
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