Insecticidal spectrum of fluralaner to agricultural and sanitary pests

Fluralaner, as an isoxazoline insecticide, has been developed as antiparasitic (namely Bravecto) with selective toxicity for insect versus mammals. Even though the toxic effect of fluralaner to several insects have been already examined, but also more agricultural and sanitary insects should be tested before it could be used widely. Four insects, including two agricultural insects, one sanitary insect and one stored product insect were tested in the present study. Compared to the broad-spectrum and high activity insecticide of fipronil, fluralaner showed mostly higher activity to tested pests, Chao suppressalis, Tribolium castaneum, Spodoptera litura except Blattella germanica with topical application. Through summarizing and analyzing various published data, we concluded that, to date, the toxic activity of fluralaner to 19 insects from 11 orders were already examined, and fluralaner displayed excellent activity. Compared to fipronil, fluralaner mostly shows more excellent activity to tested insect with maximal 1.67 x 10(4)-fold difference so much. In the present study, the toxicity activity of fluralaner was compared to the broad-spectrum phenylpyrazole insecticide fipronil to tested insect pests and the results exhibited that fluralaner would be a novel alternative insecticide with broad insecticidal spectrum and be widely used in more other areas not only as veterinary drug.